{"id":17,"date":"2026-03-23T10:20:04","date_gmt":"2026-03-23T09:20:04","guid":{"rendered":"https:\/\/crseh.com\/ja\/2026\/03\/23\/%e5%97%85%e8%a6%9a%e3%81%ae%e5%96%aa%e5%a4%b1%e3%81%af%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85%e3%81%ae%e5%88%9d%e6%9c%9f%e5%85%86%e5%80%99%e3%82%92%e6%98%8e%e3%82%89\/"},"modified":"2026-03-23T10:21:50","modified_gmt":"2026-03-23T09:21:50","slug":"%e5%97%85%e8%a6%9a%e3%81%ae%e5%96%aa%e5%a4%b1%e3%81%af%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85%e3%81%ae%e5%88%9d%e6%9c%9f%e5%85%86%e5%80%99%e3%82%92%e6%98%8e%e3%82%89","status":"publish","type":"post","link":"https:\/\/crseh.com\/ja\/2026\/03\/23\/%e5%97%85%e8%a6%9a%e3%81%ae%e5%96%aa%e5%a4%b1%e3%81%af%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85%e3%81%ae%e5%88%9d%e6%9c%9f%e5%85%86%e5%80%99%e3%82%92%e6%98%8e%e3%82%89\/","title":{"rendered":"\u55c5\u899a\u306e\u55aa\u5931\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u521d\u671f\u5146\u5019\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u304b\uff1f"},"content":{"rendered":"

\u55c5\u899a\u306e\u55aa\u5931\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u521d\u671f\u5146\u5019\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u304b\uff1f<\/h1>\n

\u9f3b\u306e\u7d30\u80de\u306e\u7c21\u5358\u306a\u751f\u691c\u304c\u3001\u8a8d\u77e5\u75c7\u72b6\u304c\u73fe\u308c\u308b\u306f\u308b\u304b\u524d\u306b\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u3054\u304f\u521d\u671f\u6bb5\u968e\u3092\u691c\u51fa\u3059\u308b\u624b\u52a9\u3051\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u7814\u7a76\u8005\u305f\u3061\u306f\u3001\u75c5\u6c17\u306e\u3055\u307e\u3056\u307e\u306a\u6bb5\u968e\u306b\u3042\u308b\u4eba\u3005\u3001\u304a\u3088\u3073\u5065\u5eb7\u3067\u306f\u3042\u308b\u304c\u75c5\u6c17\u306e\u751f\u7269\u5b66\u7684\u30de\u30fc\u30ab\u30fc\u3092\u6301\u3064\u500b\u4eba\u304b\u3089\u63a1\u53d6\u3057\u305f\u55c5\u7c98\u819c\u306e\u30b5\u30f3\u30d7\u30eb\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002\u5f7c\u3089\u306e\u7814\u7a76\u306f\u3001\u3053\u306e\u5bb9\u6613\u306b\u30a2\u30af\u30bb\u30b9\u53ef\u80fd\u306a\u9818\u57df\u304c\u3001\u75c5\u6c17\u306b\u7279\u5fb4\u7684\u306a\u708e\u75c7\u304a\u3088\u3073\u795e\u7d4c\u5909\u5316\u3092\u53cd\u6620\u3057\u3066\u304a\u308a\u3001\u975e\u4fb5\u8972\u7684\u3067\u65e9\u671f\u306e\u8a3a\u65ad\u3078\u306e\u9053\u3092\u958b\u304f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u9f3b\u306e\u4e0a\u90e8\u306b\u4f4d\u7f6e\u3059\u308b\u55c5\u7c98\u819c\u306b\u306f\u3001\u8133\u306b\u76f4\u63a5\u3064\u306a\u304c\u308b\u611f\u899a\u30cb\u30e5\u30fc\u30ed\u30f3\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u60a3\u8005\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u3001\u5f71\u97ff\u3092\u53d7\u3051\u305f\u8133\u9818\u57df\u3067\u89b3\u5bdf\u3055\u308c\u308b\u3082\u306e\u3068\u540c\u69d8\u306e\u7570\u5e38\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u84c4\u7a4d\u3057\u307e\u3059\u3002\u79d1\u5b66\u8005\u305f\u3061\u306f\u3001\u9ad8\u5ea6\u306a\u7d30\u80de\u5206\u6790\u6280\u8853\u3092\u7528\u3044\u3066\u3001\u660e\u3089\u304b\u306a\u8a8d\u77e5\u969c\u5bb3\u306f\u306a\u3044\u3082\u306e\u306e\u75c5\u6c17\u306e\u751f\u7269\u5b66\u7684\u30de\u30fc\u30ab\u30fc\u3092\u6301\u3064\u500b\u4eba\u3067\u3082\u3001\u3053\u306e\u7c98\u819c\u306b\u708e\u75c7\u3084\u795e\u7d4c\u30b9\u30c8\u30ec\u30b9\u306e\u521d\u671f\u5146\u5019\u3092\u7279\u5b9a\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u3053\u306e\u7814\u7a76\u306f\u3001\u5065\u5eb7\u306a\u6210\u4eba\u3001\u8a8d\u77e5\u75c7\u72b6\u3092\u6301\u3064\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u60a3\u8005\u3001\u305d\u3057\u3066\u75c7\u72b6\u306f\u306a\u3044\u304c\u8133\u810a\u9ac4\u6db2\u306b\u7570\u5e38\u304c\u3042\u308b\u524d\u81e8\u5e8a\u6bb5\u968e\u306e\u6210\u4eba\u306e3\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u3092\u5bfe\u8c61\u306b\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u7279\u306bT\u30ea\u30f3\u30d1\u7403\u306a\u3069\u306e\u514d\u75ab\u7d30\u80de\u306e\u7570\u5e38\u306a\u6d3b\u6027\u5316\u3084\u3001\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u578b\u7d30\u80de\u306b\u304a\u3051\u308b\u708e\u75c7\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u5897\u52a0\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u5909\u5316\u306f\u524d\u81e8\u5e8a\u6bb5\u968e\u304b\u3089\u89b3\u5bdf\u3055\u308c\u3001\u75c5\u6c17\u306e\u9032\u884c\u3068\u3068\u3082\u306b\u5f37\u307e\u308a\u307e\u3059\u3002<\/p>\n

\u55c5\u899a\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u5302\u3044\u306e\u691c\u51fa\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u708e\u75c7\u3084\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5897\u52a0\u3057\u3001\u4fdd\u8b77\u7684\u306a\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u6e1b\u5c11\u3059\u308b\u306a\u3069\u3001\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u306e\u5909\u5316\u3082\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5909\u5316\u306f\u3001\u30cb\u30e5\u30fc\u30ed\u30f3\u3068\u514d\u75ab\u7d30\u80de\u9593\u306e\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u304c\u4e71\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3001\u795e\u7d4c\u5909\u6027\u306b\u5bc4\u4e0e\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u9f3b\u306e\u30b5\u30f3\u30d7\u30eb\u3092\u5206\u6790\u3059\u308b\u3053\u3068\u3067\u3001\u75c5\u6c17\u306e\u9032\u884c\u3092\u8ffd\u8de1\u3057\u3001\u6cbb\u7642\u306e\u6f5c\u5728\u7684\u306a\u6a19\u7684\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u751f\u304d\u305f\u8133\u3067\u306f\u89b3\u5bdf\u304c\u96e3\u3057\u3044\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u521d\u671f\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u7814\u7a76\u3059\u308b\u5b9f\u7528\u7684\u306a\u624b\u6bb5\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u8840\u6db2\u691c\u67fb\u3084\u753b\u50cf\u8a3a\u65ad\u306a\u3069\u306e\u73fe\u5728\u306e\u691c\u67fb\u3092\u88dc\u5b8c\u3057\u3001\u60a3\u8005\u306e\u8a3a\u65ad\u3068\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u3092\u7cbe\u5bc6\u5316\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n

\u8981\u7d04\u3059\u308b\u3068\u3001\u55c5\u7c98\u819c\u306f\u8133\u3078\u306e\u7a93\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001\u75c7\u72b6\u304c\u73fe\u308c\u308b\u306f\u308b\u304b\u524d\u306b\u75c5\u7684\u30d7\u30ed\u30bb\u30b9\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3059\u3002\u3053\u306e\u767a\u898b\u306f\u3001\u3088\u308a\u65e9\u671f\u3067\u7684\u3092\u7d5e\u3063\u305f\u4ecb\u5165\u3092\u53ef\u80fd\u306b\u3057\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u7ba1\u7406\u3092\u5909\u9769\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\n

Attributions et sources<\/h2>\n

Origine de l\u2019\u00e9tude<\/h3>\n

DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1038\/s41467-026-70099-7<\/a><\/p>\n

Titre\u00a0:<\/strong> Olfactory cleft biopsy analysis of Alzheimer\u2019s disease pathobiology across disease stages<\/p>\n

Revue : <\/strong> Nature Communications<\/p>\n

\u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n

Auteurs : <\/strong> Vincent M. D\u2019Anniballe; Sarah Kim; John B. Finlay; Michael Wang; Tiffany Ko; Sheng Luo; Heather E. Whitson; Kim G. Johnson; Bradley J. Goldstein<\/p>\n","protected":false},"excerpt":{"rendered":"

\u55c5\u899a\u306e\u55aa\u5931\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u521d\u671f\u5146\u5019\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u304b\uff1f \u9f3b\u306e\u7d30\u80de\u306e\u7c21\u5358\u306a\u751f\u691c\u304c\u3001\u8a8d\u77e5\u75c7\u72b6\u304c\u73fe\u308c\u308b\u306f\u308b\u304b\u524d\u306b\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u3054\u304f\u521d\u671f\u6bb5\u968e\u3092\u691c\u51fa\u3059\u308b\u624b\u52a9\u3051\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u7814\u7a76\u8005\u305f\u3061\u306f\u3001\u75c5\u6c17\u306e\u3055\u307e\u3056\u307e\u306a\u6bb5\u968e\u306b\u3042\u308b\u4eba… \u7d9a\u304d\u3092\u8aad\u3080 \u55c5\u899a\u306e\u55aa\u5931\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u521d\u671f\u5146\u5019\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u304b\uff1f<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-17","post","type-post","status-publish","format-standard","hentry","category-2","entry"],"_links":{"self":[{"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/posts\/17","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/comments?post=17"}],"version-history":[{"count":1,"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/posts\/17\/revisions"}],"predecessor-version":[{"id":18,"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/posts\/17\/revisions\/18"}],"wp:attachment":[{"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/media?parent=17"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/categories?post=17"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/crseh.com\/ja\/wp-json\/wp\/v2\/tags?post=17"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}