{"id":17,"date":"2026-06-16T10:49:49","date_gmt":"2026-06-16T08:49:49","guid":{"rendered":"https:\/\/crseh.com\/ko\/2026\/06\/16\/%ed%98%88%ec%95%a1-%eb%82%b4-%ec%84%b8%ed%8f%ac-%eb%85%b8%ed%99%94-%ec%a7%88%eb%b3%91-%ec%9c%84%ed%97%98%ec%9d%84-%eb%93%9c%eb%9f%ac%eb%82%b4%eb%8b%a4\/"},"modified":"2026-06-16T10:51:07","modified_gmt":"2026-06-16T08:51:07","slug":"%ed%98%88%ec%95%a1-%eb%82%b4-%ec%84%b8%ed%8f%ac-%eb%85%b8%ed%99%94-%ec%a7%88%eb%b3%91-%ec%9c%84%ed%97%98%ec%9d%84-%eb%93%9c%eb%9f%ac%eb%82%b4%eb%8b%a4","status":"publish","type":"post","link":"https:\/\/crseh.com\/ko\/2026\/06\/16\/%ed%98%88%ec%95%a1-%eb%82%b4-%ec%84%b8%ed%8f%ac-%eb%85%b8%ed%99%94-%ec%a7%88%eb%b3%91-%ec%9c%84%ed%97%98%ec%9d%84-%eb%93%9c%eb%9f%ac%eb%82%b4%eb%8b%a4\/","title":{"rendered":"\ud608\uc561 \ub0b4 \uc138\ud3ec \ub178\ud654, \uc9c8\ubcd1 \uc704\ud5d8\uc744 \ub4dc\ub7ec\ub0b4\ub2e4"},"content":{"rendered":"

\"\ud608\uc561“`html<\/p>\n

\ud608\uc561 \ub0b4 \uc138\ud3ec \ub178\ud654, \uc9c8\ubcd1 \uc704\ud5d8\uc744 \ub4dc\ub7ec\ub0b4\ub2e4<\/h1>\n

6\ub9cc \uba85\uc5d0\uc11c 7,000\uac1c \uc774\uc0c1\uc758 \ud608\uc7a5 \ub2e8\ubc31\uc9c8\uc744 \uc2ec\uce35 \ubd84\uc11d\ud55c \uacb0\uacfc, \uc2e0\uacbd \uc138\ud3ec\ubd80\ud130 \uadfc\uc721 \uc138\ud3ec, \uba74\uc5ed \uc138\ud3ec\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 40\uc5ec \uc885\ub958 \uc774\uc0c1\uc758 \uc138\ud3ec \uc720\ud615\uc758 \uc0dd\ubb3c\ud559\uc801 \ub098\uc774\ub97c \ucd94\uc815\ud560 \uc218 \uc788\ub294 \ubaa8\ub378\uc774 \uac1c\ubc1c\ub418\uc5c8\ub2e4. \uc5f0\uad6c \uacb0\uacfc\uc5d0 \ub530\ub974\uba74 \ub178\ud654\ub294 \ubaa8\ub4e0 \uc138\ud3ec\uc5d0 \ub3d9\uc77c\ud558\uac8c \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc774 \uc544\ub2c8\ub77c, 20~25%\uc758 \uc0ac\ub78c\ub4e4\uc774 \ub2e8 \ud55c \uac00\uc9c0 \uc138\ud3ec \uc720\ud615\uc5d0\uc11c \uac00\uc18d\ud654\ub41c \ub178\ud654\ub97c \ubcf4\uc774\uba70, 1~3%\ub294 \ucd5c\uc18c \uc5f4 \uac00\uc9c0 \uc138\ud3ec\uc5d0\uc11c \ub178\ud654\uac00 \uac00\uc18d\ud654\ub418\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \uc138\ud3ec \ub178\ud654\uc758 \ud2b9\uc9d5\uc740 15\ub144 \ub3d9\uc548 \uc9c8\ubcd1 \ubc1c\uc0dd\uacfc \uc0ac\ub9dd\ub960\uacfc \ubc00\uc811\ud55c \uc5f0\uad00\uc131\uc774 \uc788\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uc704\ud5d8\uc744 \ub192\uc774\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc9c4 APOE4 \uc720\uc804\uc790\ub97c \uac00\uc9c4 \uc0ac\ub78c\ub4e4\uc740 \ubcc4\uc138\ud3ec(\ub1cc \uc138\ud3ec\uc758 \ud55c \uc885\ub958)\uc5d0\uc11c \uac00\uc18d\ud654\ub41c \ub178\ud654\ub97c \ubcf4\uc778 \ubc18\uba74, \ub300\uc2dd\uc138\ud3ec(\uba74\uc5ed \uc138\ud3ec)\uc5d0\uc11c\ub294 \uc0c1\ub300\uc801\uc73c\ub85c \uc80a\uc740 \uc0c1\ud0dc\ub97c \uc720\uc9c0\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \ubc18\ub300\ub85c APOE2 \uc720\uc804\uc790\ub97c \uac00\uc9c4 \uc0ac\ub78c\ub4e4\uc740 \ubc18\ub300\ub418\ub294 \ud504\ub85c\ud30c\uc77c\uc744 \ubcf4\uc774\uba70, \ubcc4\uc138\ud3ec\ub294 \ub354 \uc80a\uace0 \ub300\uc2dd\uc138\ud3ec\ub294 \ub354 \ub178\ud654\ub418\uc5b4 \uc788\ub2e4. \uc774\ub7ec\ud55c \ucc28\uc774\ub294 APOE4 \uc720\uc804\uc790\uac00 \uba74\uc5ed \uac10\uc2dc \uae30\ub2a5\uc744 \uac15\ud654\ud558\uc5ec \uacfc\uac70 \ubcd1\uc6d0\uccb4\uc5d0 \ub300\ud55c \uc0dd\uc874 \uc774\uc810\uc744 \uc81c\uacf5\ud588\uc9c0\ub9cc, \uadf8 \ub300\uac00\ub85c \ub1cc\uc758 \uac00\uc18d\ud654\ub41c \ub178\ud654\ub97c \ucd08\ub798\ud55c \uc9c4\ud654\uc801 \uba54\ucee4\ub2c8\uc998\uc73c\ub85c \uc124\uba85\ub420 \uc218 \uc788\ub2e4.<\/p>\n

\ubcc4\uc138\ud3ec\uc758 \uadf9\uc2ec\ud55c \ub178\ud654\ub294 APOE4 \uc720\uc804\uc790\ub97c \ub450 \ubcf5\uc0ac\ubcf8 \uac00\uc9c4 \uc0ac\ub78c\ub4e4\uc5d0\uac8c\uc11c \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ubc1c\ubcd1 \uc704\ud5d8\uc744 3\ubc30\ub098 \uc99d\uac00\uc2dc\ud0a4\uba70, \uac19\uc740 \uc138\ud3ec\uc758\u5e74\u8f7b\ud654\ub294 \uc774 \uc704\ud5d8\uc744 \uc720\uc758\ubbf8\ud558\uac8c \uac10\uc18c\uc2dc\ud0a8\ub2e4. \ub610\ud55c, \uace8\uaca9\uadfc \uc138\ud3ec\uc758 \uc2ec\ud55c \ub178\ud654\ub294 \uadfc\uc704\ucd95\uc131 \uce21\uc0c9\uacbd\ud654\uc99d(\uc911\uc99d \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658)\uc758 \uc704\ud5d8\uc744 12.7\ubc30\ub098 \uc99d\uac00\uc2dc\ud0a8\ub2e4. \ud761\uc5f0\uc790\uc758 \uacbd\uc6b0, \ud638\ud761\uae30 \uc0c1\ud53c \uc138\ud3ec\uc758 \uac00\uc18d\ud654\ub41c \ub178\ud654\ub294 \ud761\uc5f0\ub9cc\uc73c\ub85c \uc778\ud55c \ud3d0\uc554 \uc704\ud5d8\uc744 58%\ub098 \ub354 \uc99d\uac00\uc2dc\ud0a8\ub2e4.<\/p>\n

\uc138\ud3ec \ub178\ud654\uc758 \ud2b9\uc9d5\uc740 \ub2e4\ub978 \uc9c8\ubcd1\ub3c4 \uc608\uce21\ud560 \uc218 \uc788\ub2e4. \ud3d0 \uc218\ub9ac\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 2\ud615 \ud3d0\ud3ec \uc138\ud3ec\uc758 \uadf9\uc2ec\ud55c \ub178\ud654\ub294 \ube44\ud761\uc5f0\uc790\uc5d0\uc11c\ub3c4 \ud3d0\uc554 \uc704\ud5d8\uc744 \ub192\uc774\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \ub610\ud55c, 2\ud615 \ub2f9\ub1e8\ubcd1\uc758 \uacbd\uc6b0, \uc5fc\uc99d\uacfc \uad00\ub828\ub41c \uace8\uc218 \uacc4\uc5f4 \uc138\ud3ec\uc758 \uc2ec\ud55c \ub178\ud654\ub294 \ud608\ub2f9 \uc218\uce58\uc640 \uac19\uc740 \uc804\ud1b5\uc801\uc778 \uc704\ud5d8 \uc694\uc778\uc774 \uc5c6\ub354\ub77c\ub3c4 \uc704\ud5d8\uc744 \uc720\uc758\ubbf8\ud558\uac8c \uc99d\uac00\uc2dc\ud0a8\ub2e4.<\/p>\n

\uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc0dd\ud65c \ubc29\uc2dd\uc774 \uc138\ud3ec \ub178\ud654\uc5d0 \uc9c1\uc811\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4. \uae08\uc5f0, \uc808\uc81c\ub41c \uc74c\uc8fc, \uc815\uc0c1 \uccb4\uc9c8\ub7c9 \uc9c0\uc218, \uaddc\uce59\uc801\uc778 \uc2e0\uccb4 \ud65c\ub3d9, \ucda9\ubd84\ud55c \uc218\uba74\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud558\ub294 \uac74\uac15\ud55c \uc0dd\ud65c \ubc29\uc2dd\uc744 \uc720\uc9c0\ud558\ub294 \uc0ac\ub78c\ub4e4\uc740 \uc804\ubc18\uc801\uc73c\ub85c \ub354 \uc80a\uc740 \uc138\ud3ec\ub97c \uac00\uc9c0\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\ub2e4. \ubc18\ub300\ub85c \ud761\uc5f0\uacfc \ube44\ub9cc\uc774 \uacb0\ud569\ub41c \uc0ac\ub78c\ub4e4\uc740 \ub9ce\uc740 \uc138\ud3ec \uc720\ud615\uc5d0\uc11c \uac00\uc18d\ud654\ub41c \ub178\ud654\ub97c \ubcf4\uc778\ub2e4.<\/p>\n

\uc138\ud3ec \ub178\ud654\uc758 \ub204\uc801 \ubd80\ud558\ub294 \uc0dd\uc874\uc5d0 \ud070 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4. 20\uac1c \uc774\uc0c1\uc758 \uc138\ud3ec \uc720\ud615\uc5d0\uc11c \uac00\uc18d\ud654\ub41c \ub178\ud654\ub97c \ubcf4\uc778 \uc0ac\ub78c\ub4e4\uc758 15\ub144 \uc0dd\uc874\uc728\uc740 \uc57d 34%\uc5d0 \ubd88\uacfc\ud55c \ubc18\uba74, \uc138\ud3ec\uac00 \uc815\uc0c1\uc801\uc73c\ub85c \ub178\ud654\ub41c \uc0ac\ub78c\ub4e4\uc758 \uc0dd\uc874\uc728\uc740 90%\uc5d0 \ub2ec\ud55c\ub2e4. \ubc18\ub300\ub85c, \uba74\uc5ed \uc138\ud3ec\ub098 \uc2e0\uacbd \uc138\ud3ec\uc758 \uc80a\uc740\ud654\ub294 \uc218\uba85\uc744 \uc5f0\uc7a5\uc2dc\ud0a8\ub2e4. \ub2e4\uc138\ud3ec \uc704\ud5d8 \uc810\uc218\uac00 \uac1c\ubc1c\ub418\uc5b4 \uc0ac\ub9dd \uc704\ud5d8\uc744 \uce35\ud654\ud558\ub294 \ub370 \uc0ac\uc6a9\ub418\uba70, \ub2e4\uc591\ud55c \ub2e8\ubc31\uc9c8 \ubd84\uc11d \ud50c\ub7ab\ud3fc\uc5d0\uc11c \uac15\ub825\ud55c \uc608\uce21 \ub2a5\ub825\uc744 \uc785\uc99d\ud558\uc600\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \ubc1c\uacac\ub4e4\uc740 \uc138\ud3ec \uc218\uc900\uc5d0\uc11c \uc778\uac04 \ub178\ud654\ub97c \uc774\ud574\ud558\ub294 \uc0c8\ub85c\uc6b4 \ubc29\ubc95\uc744 \uc81c\uacf5\ud55c\ub2e4. \uc774\ub294 \uc9c8\ubcd1 \uc704\ud5d8\uc744 \ud3c9\uac00\ud558\uace0, \uac00\uc7a5 \ucde8\uc57d\ud55c \uc138\ud3ec \uc720\ud615\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \uc7a0\uc7ac\uc801\uc778 \uce58\ub8cc \ud45c\uc801\uc744 \uc2dd\ubcc4\ud558\ub294 \uac1c\uc778 \ub9de\ucda4\ud615 \uc811\uadfc \ubc29\uc2dd\uc744 \uc5f4\uac8c \ub41c\ub2e4. \ub178\ud654\ub294 \ub354 \uc774\uc0c1 \uade0\uc77c\ud55c \uacfc\uc815\uc73c\ub85c \ubcf4\uae30\ub294 \uc5b4\ub824\uc6b0\uba70, \uac01\uae30 \ub2e4\ub978 \uac74\uac15\uacfc \uc9c8\ubcd1\uc5d0 \uae30\uc5ec\ud558\ub294 \ub3c5\ud2b9\ud55c \uc138\ud3ec \uacbd\ub85c\uc758 \ubaa8\uc790\uc774\ud06c\ub85c \uc774\ud574\ub418\uc5b4\uc57c \ud55c\ub2e4.<\/p>\n

“`<\/p>\n

\n

Attributions et sources<\/h2>\n

Origine de l\u2019\u00e9tude<\/h3>\n

DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1038\/s41591-026-04446-y<\/a><\/p>\n

Titre\u00a0:<\/strong> Plasma proteomic signatures of cellular aging predict human disease<\/p>\n

Revue : <\/strong> Nature Medicine<\/p>\n

\u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n

Auteurs : <\/strong> Daisy Yi Ding; Veronica Augustina Bot; Kenneth L. Chen; James W. Groves; R\u00f3bert P\u00e1lovics; Daisuke Masuda; Amelia Farinas; Hamilton Se-Hwee Oh; Viktoria Wagner; Nannan Lu; ; Carlos Cruchaga; Alina Isakova; Jonathan M. Schott; Tony Wyss-Coray<\/p>\n","protected":false},"excerpt":{"rendered":"

“`html \ud608\uc561 \ub0b4 \uc138\ud3ec \ub178\ud654, \uc9c8\ubcd1 \uc704\ud5d8\uc744 \ub4dc\ub7ec\ub0b4\ub2e4 6\ub9cc \uba85\uc5d0\uc11c 7,000\uac1c \uc774\uc0c1\uc758 \ud608\uc7a5 \ub2e8\ubc31\uc9c8\uc744 \uc2ec\uce35 \ubd84\uc11d\ud55c \uacb0\uacfc, \uc2e0\uacbd \uc138\ud3ec\ubd80\ud130 \uadfc\uc721 \uc138\ud3ec, \uba74\uc5ed \uc138\ud3ec\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 40\uc5ec \uc885\ub958 \uc774\uc0c1\uc758 \uc138\ud3ec \uc720\ud615\uc758 \uc0dd\ubb3c\ud559\uc801 \ub098\uc774\ub97c \ucd94\uc815\ud560 \uc218 \uc788\ub294 \ubaa8\ub378\uc774 \uac1c\ubc1c\ub418\uc5c8\ub2e4. \uc5f0\uad6c \uacb0\uacfc\uc5d0 \ub530\ub974\uba74 \ub178\ud654\ub294 \ubaa8\ub4e0 \uc138\ud3ec\uc5d0 \ub3d9\uc77c\ud558\uac8c \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc774 \uc544\ub2c8\ub77c, 20~25%\uc758 \uc0ac\ub78c\ub4e4\uc774 \ub2e8 \ud55c \uac00\uc9c0 \uc138\ud3ec \uc720\ud615\uc5d0\uc11c \uac00\uc18d\ud654\ub41c… \ud608\uc561 \ub0b4 \uc138\ud3ec \ub178\ud654, \uc9c8\ubcd1 \uc704\ud5d8\uc744 \ub4dc\ub7ec\ub0b4\ub2e4<\/span> \uacc4\uc18d \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,3],"tags":[],"class_list":["post-17","post","type-post","status-publish","format-standard","hentry","category-2","category-3","entry"],"_links":{"self":[{"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/posts\/17","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/comments?post=17"}],"version-history":[{"count":1,"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/posts\/17\/revisions"}],"predecessor-version":[{"id":18,"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/posts\/17\/revisions\/18"}],"wp:attachment":[{"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/media?parent=17"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/categories?post=17"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/crseh.com\/ko\/wp-json\/wp\/v2\/tags?post=17"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}